Every program below was checked by hand on August 5, 2026 on the hospital’s own website. A center is listed only when the hospital itself names a mesothelioma program, a mesothelioma specialty group, or a peritoneal HIPEC program.
The one thing most lists get wrong
Many “best hospitals for mesothelioma” lists are really lists of NCI-designated cancer centers. That designation is a research credential from the National Cancer Institute. It is a genuine mark of quality — but it does not tell you whether that hospital has anyone who treats mesothelioma regularly. There are more than 70 NCI-designated centers. Far fewer run a named mesothelioma program.
So this directory asks a narrower question: does this hospital say, in its own words, that it has a mesothelioma program?
Pleural or peritoneal decides which surgeon you need
This is the detail that costs families the most time. Mesothelioma in the lining of the chest (pleural) is treated by thoracic surgeons. Mesothelioma in the lining of the abdomen (peritoneal) is treated by surgical oncologists who perform cytoreductive surgery with heated chemotherapy, called HIPEC. They are different specialists in different departments — sometimes at different hospitals.
If you are not certain which type is on the pathology report, ask before you book. A MesoCare Patient Advocate can help you read it: call 1-800-877-6000.
What to ask when you call any of them
- How many people with mesothelioma does this program see in a year?
- Who would lead my family member’s care, and what is their experience with this diagnosis?
- Do you offer a second-opinion review of outside pathology and scans?
- Are there clinical trials open here right now for this type and stage?
- How soon could we be seen, and what records do you need first?
Centers treating both pleural and peritoneal mesothelioma
These programs see both forms, which can matter if the diagnosis is still being confirmed.
Memorial Sloan Kettering Cancer Center — Mesothelioma care program
New York, NY
- Treats: Both pleural (chest) and peritoneal (abdomen)
- MSK states it treats one of the nation’s largest volumes of mesothelioma patients.
- Treats both pleural and peritoneal mesothelioma.
- A multidisciplinary team meets twice monthly to set treatment strategy for individual patients.
- Phone: 800-525-2225
- Program page: mskcc.org
Mayo Clinic — Mesothelioma Specialty Group
Rochester, MN
- Treats: Both pleural (chest) and peritoneal (abdomen)
- A named mesothelioma specialty group, explicitly covering both pleural and peritoneal mesothelioma.
- Multidisciplinary care including surgery, radiation and chemotherapy.
- Mayo Clinic also has campuses in Arizona and Florida.
- Program page: mayoclinic.org
Cleveland Clinic — Mesothelioma treatment program
Cleveland, OH
- Treats: Both pleural (chest) and peritoneal (abdomen)
- One of a small number of U.S. programs offering comprehensive mesothelioma treatment.
- Was among the first U.S. programs to use HIPEC (heated chemotherapy) for mesothelioma affecting the abdominal lining.
- Multidisciplinary team spanning pulmonology, medical oncology, thoracic surgery and radiation oncology.
- Phone: 844-365-7735
- Program page: my.clevelandclinic.org
City of Hope — Mesothelioma clinical program
Los Angeles / Duarte, CA
- Treats: Both pleural (chest) and peritoneal (abdomen)
- A named mesothelioma clinical program, plus a separate peritoneal surface malignancies service.
- Offers minimally invasive laparoscopic and robotic surgery, intrapleural as well as systemic chemotherapy, targeted therapy and tumor treating fields.
- Runs mesothelioma clinical trials in immunotherapy and targeted therapy.
- Program page: cityofhope.org
Centers with a pleural (chest) mesothelioma program
Pleural mesothelioma is the more common form. These programs are built around thoracic — chest — surgery and care.
Brigham and Women’s Hospital — International Mesothelioma Program (IMP)
Boston, MA
- Treats: Pleural mesothelioma (chest lining)
- Founded in 2002; the hospital describes it as the largest program of its kind in the world.
- A joint effort across Brigham and Women’s, Dana-Farber Cancer Institute, Massachusetts General Hospital, the Boston VA Health Care System and the Harvard School of Public Health.
- Care spans surgery, chemotherapy, radiation, rehabilitation, post-acute care and supportive services, with a dedicated multidisciplinary team.
- Program page: brighamandwomens.org
MD Anderson Cancer Center — Thoracic Center — mesothelioma care
Houston, TX
- Treats: Pleural mesothelioma (chest lining)
- Offers both pleurectomy/decortication and extrapleural pneumonectomy for pleural mesothelioma.
- Clinical trials include immunotherapy and targeted radiation.
- Mesothelioma patients can also be seen at the League City, Sugar Land, The Woodlands and West Houston locations.
- Phone: 1-877-632-6789
- Program page: mdanderson.org
Penn Medicine — Abramson Cancer Center — Mesothelioma and Pleural Disease Program
Philadelphia, PA
- Treats: Pleural mesothelioma (chest lining)
- A named, dedicated mesothelioma and pleural disease program.
- A leader in photodynamic therapy for mesothelioma, and a major site for mesothelioma clinical trials.
- Assigns dedicated social workers, a mesothelioma advanced-practice provider and a program coordinator who help with scheduling and transportation.
- Program page: pennmedicine.org
Moffitt Cancer Center — Mesothelioma Research and Treatment Center
Tampa, FL
- Treats: Pleural mesothelioma (chest lining)
- A named mesothelioma research and treatment center with a team focused on mesothelioma.
- Explores immunotherapy, gene therapy and photodynamic therapy through its Thoracic Oncology Program.
- States it is the only cancer center offering transarterial chemoperfusion to mesothelioma patients.
- Phone: 1-888-663-3488
- Program page: moffitt.org
UCSF Health — Thoracic Surgery & Oncology
San Francisco, CA
- Treats: Pleural mesothelioma (chest lining)
- One of the most experienced thoracic programs on the West Coast; mesothelioma is a named specialty of multiple faculty.
- Dr. Matthew Gubens, Medical Director of Thoracic Medical Oncology, serves on the National Comprehensive Cancer Network (NCCN) mesothelioma panel — the group that writes the national treatment guidelines.
- Offers targeted therapy and immunotherapy, with an active thoracic clinical-trials program.
- Program page: ucsfhealth.org
AdventHealth Orlando — Thoracic Surgery — AdventHealth Cancer Institute
Orlando, FL
- Treats: Pleural mesothelioma (chest lining)
- Dr. Marcelo C. DaSilva is Medical Director of Thoracic Surgery for AdventHealth Orlando.
- He came to Central Florida from Boston, where he was a thoracic surgeon at Brigham and Women’s Hospital and a Lecturer in Surgery at Harvard Medical School.
- Practices in Orlando and Altamonte Springs; accepts new patients and offers video visits.
- Our disclosure: Dr. DaSilva is one of MesoCare’s clinical reviewers. We are naming that relationship rather than listing him as if we had no connection.
- Program page: adventhealth.com
Centers with a peritoneal (abdominal) HIPEC program
Peritoneal mesothelioma is treated by surgical oncologists who perform cytoreductive surgery with HIPEC, not by chest surgeons. If the diagnosis is peritoneal, this is the list that matters.
Mercy Medical Center — Cytoreductive surgery and HIPEC program
Baltimore, MD
- Treats: Peritoneal mesothelioma (abdominal lining)
- A dedicated peritoneal mesothelioma service within a nationally recognized cytoreductive surgery and HIPEC program.
- Surgeons Dr. Armando Sardi, Dr. Vadim Gushchin and Dr. Kurtis Campbell lead the program.
- Mercy performs two to three cytoreductive surgery/HIPEC operations per week.
- Program page: mdmercy.com
Atrium Health Wake Forest Baptist — Peritoneal Surface Malignancy Program
Winston-Salem, NC
- Treats: Peritoneal mesothelioma (abdominal lining)
- An internationally known peritoneal surface malignancy program treating advanced abdominal cancer with cytoreductive surgery plus HIPEC.
- The center has performed more than 1,100 HIPEC procedures — one of the most experienced teams worldwide.
- Dr. Edward A. Levine, chief of surgical oncology, is a recognized national leader in HIPEC.
- Program page: wakehealth.edu
What we left out, and why
Leaving things out honestly is part of what makes a directory useful:
- Miracle Flights — Free flights, but only for patients aged 0–17. Mesothelioma is overwhelmingly diagnosed in older adults, so it does not apply to almost any mesothelioma family. Listed here so nobody wastes a phone call.
- Patient AirLift Services (PALS) — Could not be verified on 2026-08-05 — the organization’s website refused automated checks. Not listed rather than listed unverified.
Help with getting there
Several of these programs are a long way from home for most families. Free flights, free lodging near treatment, and free rides to appointments all exist, and they are listed with current status in our verified grants and financial assistance directory.
For resource-page editors, social workers and nurse navigators
You are welcome to link to or cite this directory. We re-check every listing on a recurring basis and date-stamp each check, so patients aren’t sent to a program that no longer exists. Spot something we got wrong? Tell us on our contact page and we will correct it.
About this directory: compiled and verified by MesoCare.org, last full verification August 5, 2026. MesoCare is sponsored by Danziger & De Llano. This page is educational and is not medical advice. We do not rank these programs, recommend one over another, or reproduce survival statistics — those conversations belong with your own care team. Program details are set by each hospital and can change at any time; always confirm with the program itself.